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Arizona Cardinals vs San Francisco 49ers: Best Odds Across Every Prediction Market

NFL · Sun, Sep 27, 2026 at 4:05 PM EDT

San Francisco 49ers is favored at -388. Below is the live moneyline for Arizona Cardinals vs San Francisco 49ers compared across Kalshi, Polymarket, ProphetX, BettorEdge, BetOpenly, SX Bet and more, with the best price on each side marked so you take the highest payout.

Arizona Cardinals vs San Francisco 49ers odds: best price across every platform

Best price on each side

Best price on
Arizona Cardinals
+351
ProphetX · 22% implied
Best price on
San Francisco 49ers
-388
Polymarket · 80% implied

Arizona Cardinals vs San Francisco 49ers odds by platform

PlatformARISF
Kalshi+331-404
Polymarket+344-388
ProphetX+351-389

American odds shown. Best payout on each side highlighted. Prices update live.

Kalshi vs Polymarket: Arizona Cardinals vs San Francisco 49ers

Kalshi and Polymarket frequently price the same game differently, and neither is consistently sharper. The table above shows where each side is cheapest right now. On OpenMarkets you can see all venues at once, including ProphetX, BettorEdge, BetOpenly, SX Bet and more, and route to the best number instead of guessing which platform leads on a given market.

How to read these odds

Each price reflects the implied probability of an outcome. A lower price (further from even) means a higher payout if that side wins. Because Kalshi, Polymarket, ProphetX, BettorEdge, BetOpenly, SX Bet and more are independent markets, the same outcome can carry different prices at the same moment. Comparing them and taking the best available number is line shopping, and over many bets that edge compounds.

FAQ

What are the best odds for Arizona Cardinals?
The best available price on Arizona Cardinals is +351 at ProphetX (22% implied probability), compared across Kalshi, Polymarket, ProphetX, BettorEdge, BetOpenly, SX Bet and more.
What are the best odds for San Francisco 49ers?
The best available price on San Francisco 49ers is -388 at Polymarket (80% implied probability).
Who is favored in Arizona Cardinals vs San Francisco 49ers?
San Francisco 49ers is the favorite, with a best price of -388 at Polymarket. Prices differ across platforms, so the best payout depends on which book you use.
Where can I get the best payout on Arizona Cardinals vs San Francisco 49ers?
OpenMarkets compares Kalshi, Polymarket, ProphetX, BettorEdge, BetOpenly, SX Bet and more in one view and marks the best price on each side, so you take the highest payout available.

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