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St. Louis Cardinals vs Pittsburgh Pirates: Best Odds Across Every Prediction Market

MLB · Tue, Sep 22, 2026 at 6:40 PM EDT

Pittsburgh Pirates is favored at -143. Below is the live moneyline for St. Louis Cardinals vs Pittsburgh Pirates compared across Kalshi, Polymarket, ProphetX, BettorEdge, BetOpenly, SX Bet and more, with the best price on each side marked so you take the highest payout.

St. Louis Cardinals vs Pittsburgh Pirates odds: best price across every platform

Best price on each side

Best price on
St. Louis Cardinals
+134
Polymarket · 43% implied
Best price on
Pittsburgh Pirates
-143
ProphetX · 59% implied

St. Louis Cardinals vs Pittsburgh Pirates odds by platform

PlatformSTLPIT
Kalshi+124-148
Polymarket+134-148
ProphetX+131-143

American odds shown. Best payout on each side highlighted. Prices update live.

Kalshi vs Polymarket: St. Louis Cardinals vs Pittsburgh Pirates

Kalshi and Polymarket frequently price the same game differently, and neither is consistently sharper. The table above shows where each side is cheapest right now. On OpenMarkets you can see all venues at once, including ProphetX, BettorEdge, BetOpenly, SX Bet and more, and route to the best number instead of guessing which platform leads on a given market.

How to read these odds

Each price reflects the implied probability of an outcome. A lower price (further from even) means a higher payout if that side wins. Because Kalshi, Polymarket, ProphetX, BettorEdge, BetOpenly, SX Bet and more are independent markets, the same outcome can carry different prices at the same moment. Comparing them and taking the best available number is line shopping, and over many bets that edge compounds.

FAQ

What are the best odds for St. Louis Cardinals?
The best available price on St. Louis Cardinals is +134 at Polymarket (43% implied probability), compared across Kalshi, Polymarket, ProphetX, BettorEdge, BetOpenly, SX Bet and more.
What are the best odds for Pittsburgh Pirates?
The best available price on Pittsburgh Pirates is -143 at ProphetX (59% implied probability).
Who is favored in St. Louis Cardinals vs Pittsburgh Pirates?
Pittsburgh Pirates is the favorite, with a best price of -143 at ProphetX. Prices differ across platforms, so the best payout depends on which book you use.
Where can I get the best payout on St. Louis Cardinals vs Pittsburgh Pirates?
OpenMarkets compares Kalshi, Polymarket, ProphetX, BettorEdge, BetOpenly, SX Bet and more in one view and marks the best price on each side, so you take the highest payout available.

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